Europe| 19:45 | Eintracht Frankfurt | - : - | Rīgas FS | |||
| 19:45 | Qarabağ | - : - | Ajax | |||
| 19:45 | Maccabi Tel Aviv | - : - | Real Sociedad | |||
| 19:45 | Midtjylland | - : - | Union Saint-Gilloise | |||
| 19:45 | PAOK | - : - | Viktoria Plzeň | |||
| 19:45 | Roma | - : - | Dynamo Kyiv | |||
| 19:45 | Ferencváros | - : - | Nice | |||
| 22:00 | Anderlecht | - : - | Ludogorets | |||
| 22:00 | Athletic Club | - : - | Slavia Praha | |||
| 22:00 | Malmö FF | - : - | Olympiakos Piraeus | |||
| 22:00 | Olympique Lyonnais | - : - | Beşiktaş | |||
| 22:00 | Porto | - : - | Hoffenheim | |||
| 22:00 | Rangers | - : - | FCSB | |||
| 22:00 | Twente | - : - | Lazio | |||
| 22:00 | Tottenham Hotspur | - : - | AZ | |||
| 22:00 | Fenerbahçe | - : - | Manchester United |
| 17:30 | Víkingur Reykjavík | - : - | Cercle Brugge | |||
| 19:45 | APOEL | - : - | Borac Banja Luka | |||
| 19:45 | Gent | - : - | Molde | |||
| 19:45 | Djurgården | - : - | Vitória Guimarães | |||
| 19:45 | Larne | - : - | Shamrock Rovers | |||
| 19:45 | Panathinaikos | - : - | Chelsea | |||
| 19:45 | Rapid Wien | - : - | Artsakh | |||
| 19:45 | St. Gallen | - : - | Fiorentina | |||
| 19:45 | Hearts | - : - | Omonia Nicosia | |||
| 19:45 | Celje | - : - | İstanbul Başakşehir | |||
| 19:45 | Jagiellonia Białystok | - : - | Petrocub | |||
| 22:00 | Paphos | - : - | Heidenheim | |||
| 22:00 | Bačka Topola | - : - | Legia Warszawa | |||
| 22:00 | Real Betis | - : - | København | |||
| 22:00 | The New Saints | - : - | Astana | |||
| 22:00 | Mladá Boleslav | - : - | Lugano | |||
| 22:00 | Olimpija | - : - | LASK | |||
| 22:00 | HJK | - : - | Dinamo Minsk |
Spain| 20:00 | Almería | - : - | Albacete | |||
| 20:00 | Levante | - : - | Deportivo La Coruña | |||
| 22:00 | Burgos | - : - | Racing Ferrol | |||
| 22:00 | Sporting Gijón | - : - | Huesca | |||
| 22:00 | Tenerife | - : - | Málaga |
